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Back to (brain) basic treatments for autism, mental retardation ...
14 Nov 2009 by e_karhu@akidway-lake.net ("Bear")  
But, after decades of painstaking basic research on how the brain rewires itself in response to external cues, Bear has discovered a way to reverse the symptoms of Fragile X Syndrome, a disorder that can cause autism, mental retardation ...
Bear Market News - http://bearmarketnews.blogspot.com/

Could Some Forms of Mental Retardation Be Treated with Drugs ...
25 Oct 2009 by edhayes  
They found similar abnormalities in dendritic spine development seen in humans with some forms of mental retardation, such as fragile X syndrome. The mice also exhibited impaired learning and memory. ...
Edmund's Page - http://edhayes.com/

Autism Related Disorders: Drosophila Drug Screen For Fragile X ...
11 Apr 2008 by Maria  
Fragile X syndrome is caused by the functional loss of the fragile X mental retardation protein (FMRP). Currently there is no effective drug therapy for fragile X syndrome, and previously no assays had been developed to screen drug ...
Autism Related Disorders - http://autismrelateddisorders.blogspot.com/ - References
[ More results from Autism Related Disorders ]

Genetic tests and personalised medicine
19 Nov 2009 by Grant Jacobs  
... skeletal deformities); Factor V-Leiden (FVL; blood-clotting disorder); Fragile X syndrome (FRAX; leading cause of inherited mental retardation); Galactosemia (GALT; metabolic disorder affects ability to metabolize galactose) ...
Code for Life - http://sciblogs.co.nz/code-for-life/

Autism and Fragile X: Differences and Intersections : Blisstree ...
6 Dec 2006 by Kristina Chew, PhD  
An anomaly in synapse formation or maintenance (which could have no consequences or be associated with isolated mental retardation); An imbalance between excitation and inhibition which could have no consequences or be associated with ...
Autism Vox - http://autismvox.com/ - References

Fragile X syndrome update : Blisstree - Family, Health, Home and ...
19 Aug 2007 by Penny  
Fragile X Syndrome (FXS) is the most common cause of inherited mental impairment. This impairment can range from learning disabilities to more severe cognitive or intellectual disabilities. (Sometimes referred to as mental retardation. ...
Genetics and Health - http://www.geneticsandhealth.com/ - References
[ More results from Genetics and Health ]

PLoS Biology: A Novel Function for Fragile X Mental Retardation ...
20 Jan 2009 by Elias G Bechara et al.  
Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein mostly involved in translational repression, may also act as a translational activator ofSod1 mRNA, suggesting that increased oxidative stress may be involved in the ...
PLoS Biology: New Articles - http://www.plosbiology.org/

In Vitro and in Cellulo Evidences for Association of the Survival ...
22 Feb 2008 by Piazzon, N., Rage, F., Schlotter, F., Moine,...  
The defective protein in Fragile X mental retardation syndrome (FMRP) also plays a role in transport of mRNPs and in their translation. Therefore, we examined possible relationships of SMN with FMRP. We observed granules containing both ...
Journal of Biological Chemistry current issue - http://www.jbc.org/
[ More results from Journal of Biological Chemistry current issue ]

Clinical tests begin on medication to correct Fragile X defect ...
2 Nov 2009 by BJS  
The work is the outcome of basic research that traced how an error in the fragile X mental retardation gene (FMR1) leads to changes in brain connections, called synapses. The changes in turn appear to be the mechanism for learning ...
Science Blog - Science news straight from... - http://www.scienceblog.com/cms/frontpage1

AJHG - Incidence of Fragile X Syndrome by Newborn Screening for ...
9 Nov 2009
The 5′ untranslated region of the fragile X mental retardation gene, , contains a polymorphic CGG repeat. Expansions of this repeat are associated with a spectrum of disorders. Full mutation alleles, repeats ≥ 200, are associated with ...
AJHG - http://www.cell.com/AJHG/top20

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